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Hydrating EGF Peptide Moisturizer

EGF Cream

EGF Cream is rated 4.7 out of 5 by 405.
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This is an intensive, skin-renewing moisturizer featuring epidermal growth factor (EGF), a peptide that encourages natural cell turnover and the production of collagen and elastin for youthful firmness and radiance.     

EGF has also been shown to even skin tone and reduce the appearance of fine lines while maintaining long-lasting hydration. 

DHC’s EGF Cream is a premium formulation that merges the power of peptides with vitamins A, C and E, plus botanicals like shea butter and cupuacu to deeply moisturize and nourish. Sodium hyaluronate, a derivative of hyaluronic acid, keeps skin well-hydrated; olive leaf extract protects against pollution; and organic olive fruit oil maintains the skin’s moisture barrier and helps fight free radical damage.

The result is a rich, luxurious cream that absorbs quickly to provide moisturizing, age-defying benefits. Your complexion is left soft, nourished and radiant.

Ideal for all skin types.

Size 1.2 oz. Net wt.
“Works wonders on my lines and seems to plump out my skin.”

Unique Features & Benefits

  • Deeply hydrates and nourishes skin with rich emollients
  • Promotes skin cell turnover and encourages collagen and elastin production for youthful-looking skin
  • Absorbs quickly; skin is left deeply hydrated with no oily residue


  • EGF (epidermal growth factor): A polypeptide made up of 53 naturally-occurring amino acids that promotes cell turnover. As our natural levels of EGF dissipate with age, our natural skin cell turnover rate slows resulting in familiar signs of aging, such as fine lines, wrinkles and loss of elasticity.
  • Hydrolyzed Collagen: Skin-firming collagen is processed into ultra-tiny peptides making it easily absorbed. Helps reduce water loss in the skin by forming a protective barrier, resulting in softer, smoother-looking skin.
  • Organic olive oil: Rich in antioxidants, it maintains the skin’s moisture barrier and helps fight free radical damage without clogging pores.
  • Shea butter: Extracted from the nuts of the karate tree, this emollient is naturally rich in vitamins and antioxidants.
Full Ingredient List

water/aqua/eau, caprylic/capric triglyceride, butylene glycol, glucose, olea europaea (olive) fruit oil, hydrogenated palm oil, stearic acid, pentylene glycol, crambe abyssinica seed oil, butyrospermum parkii (shea) butter, theobroma grandiflorum seed butter, dipalmitoyl hydroxyproline, glyceryl stearate SE, glycerin, batyl alcohol, glyceryl stearate, phenoxyethanol, behenyl alcohol, tocopherol, arginine, serine, tocotrienols, retinyl palmitate, glucosyl hesperidin, pyridoxine HCl, salix alba (willow) bark extract, arachis hypogaea (peanut) oil, ascorbyl tetraisopalmitate, hydrolyzed collagen, magnesium sulfate, sodium chloride, potassium hydroxide, ubiquinone, sodium dilauramidoglutamide lysine, peucedanum ostruthium leaf extract, sodium hyaluronate, elaeis guineensis (palm) oil, carbomer, mannitol, olea europaea (olive) leaf extract, sodium polygamma-glutamate, placental protein, polysorbate 20, pyrus malus (apple) fruit extract, soluble collagen, palmitoyl tripeptide-1, palmitoyl tetrapeptide-7, rh-oligopeptide-1

How To Use

After applying liquid lotion, smooth evenly over face.

Rated 5 out of 5 by from love the results i hardly ever write a review. EGF deserves one. I use it daily and my skin is radiant get lots of compliments for a 70 year old! Please move to simpler larger container. The jar goes in recycle or landfill anyway!
Date published: 2022-08-19
Rated 4 out of 5 by from EGF cream is one in a million EGF cream great choice for skin texture ,smoothness, and sheen
Date published: 2022-08-08
Rated 5 out of 5 by from Fantastic night cream EGF cream is worth every penny! My face loves it, and it looks and feels soft, smooth and fresh in the morning.
Date published: 2022-06-29
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All Reviews

I do not wear make-up at all and I like using DHC products. I would like to get this to help reduce the dark spots on my cheeks and to prevent dry facial skin, is it okay to use it without the liquid lotion?

Asked by: Piper C.
Hello. Our EGF Cream is chocked full of state-of -the-art ingredients that protect skin from the signs of free radical damage, improve the appearance of fine lines, intensely moisturize and encourage skin's natural cell turnover. Although it's quite possible you'll see improvement over dark spots while using EGF Cream, it's not our most comprehensive product for brightening. We recommend adding our new Age and Sun Spot Gel to your routine, applying directly to areas of concern. It's our opinion that a liquid lotion should be applied before all and any moisturizer(s). Because water makes up 70% of skin's composition, it's imperative to provide soaking hydration that a moisturizer alone cannot. When you apply a liquid lotion before moisturizer, it's much like dampening a sponge. The result is plumper skin, increased dewiness, and the perfect prep for moisturizers to absorb effectively. Thank you for choosing DHC for your skin care needs and have a beautiful day!
Answered by: DHC Beauty 1
Date published: 2022-09-05

Could this be used in the eye area? I’d love to find a moisturizer that can tackle eye areas.

Asked by: Suso176
Hello! Because the delicate tissue around the immediate eye area differs from the rest of the complexion, we are careful to only recommend eyecare products for the eye area (like Concentrated and CoQ10 Eye Creams). Although EGF Cream is excellent for tackling loss of elasticity and fine lines, its formula was developed for facial use and therefore is not recommend for use around the eyes. Thank you for choosing DHC for your skincare needs and have a beautiful day!
Answered by: DHC Beauty 1
Date published: 2022-06-23

Does ETC clog pores

Asked by: Mary E
Hello. At DHC, we strive to be transparent and realistic regarding product claims, while taking into consideration that skin types, allergies, and tolerance to ingredients differ greatly amongst individuals. "Non-comedogenic" is an industry catch-phrase referring to a product that's free of perceived pore-clogging ingredients. Because we believe there are too many variables to consider when making such a statement and the term non-comedogenic is not an FDA approved claim, we do not use it to describe our products.
Answered by: DHC Beauty 1
Date published: 2022-06-01

What is the best dark spot removing product 

Asked by: Anonymous
Hello! Although EGF Cream utilizes ingredients that can assist with overall clarity, we recommend our Vitamin C Essence for targeting dark spots. Vitamin C Essence is a very lightweight, fluid serum that uses stable, 8% magnesium ascorbyl phosphate to brighten dark spots. For best results, we recommend applying it directly to areas of concern, on freshly-cleansed skin, prior to any other skin care products; including toners, serums or moisturizers. This application technique ensures maximum absorption and benefits. To preserve your progress, we strongly encourage using our Brightening Sunscreen because it not only uses sun protection factor to avoid more dark spots, but integrates a host of brightening ingredients to tackle existing dark spots. Enjoy your products and thank you for choosing DHC for your skincare needs.
Answered by: DHC Beauty 1
Date published: 2022-06-16

Can I use this as a face cream during the day or is it strictly meant to used as a night cream?

Asked by: Emilio
Hello. Interestingly, we speak to customers who really enjoy using EGF Cream during the day and have said it works well under makeup! Although our moisturizers are versatile and can be used day and/or night, our EGF Cream uses a number of high-performance ingredients that we believe work best in the evening, during skin's natural revitalization. Should you choose to use EGF Cream during the day, we strongly recommend protecting the benefits you achieve by applying a daily sunscreen like our Brightening Sunscreen. Enjoy the product and the beauty you impart!
Answered by: DHC Beauty 1
Date published: 2021-12-15

I use a CPAP full face mask and many creams resist the mask, too oily and makes the mask leak. I need something that soaks in and then is dry on surface, so as to keep a nice seal on the silicone mask - thanks!

Asked by: KsMom
Hello. We're hesitant to recommend a product while not fully understanding the nature of a CPAP mask and suggest speaking to the physician (who prescribed its' use) for product recommendations. Perhaps you'd have better success using a hydrating serum rather than a cream. Our Beauty Lift Essence uses ceramides to strengthen skin's natural moisture barrier and is delivered in a light-weight serum that absorbs effectively, imparting dewiness without excess oil. If we can further assist you, please contact us again. Thank you for choosing DHC and have a beautiful day.
Answered by: DHC Beauty 1
Date published: 2022-07-29
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